Inselspital, University Hospital Bern: Clinical Partner in the Evolution of Directional DBS
Inselspital, University Hospital Bern: Clinical Partner in the Evolution of Directional DBS
Aleva’s collaboration with Inselspital, University Hospital Bern, has been central to the company’s clinical development from its earliest stages. Under the leadership of Co-Founder Dr Claudio Pollo, Head of Functional Neurosurgery, Inselspital served as the primary site for first-in-human trials that validated Aleva’s directional Deep Brain Stimulation system.
Aleva’s collaboration with Inselspital, University Hospital Bern, has been central to the company’s clinical development from its earliest stages. Under the leadership of Co-Founder Dr Claudio Pollo, Head of Functional Neurosurgery, Inselspital served as the primary site for first-in-human trials that validated Aleva’s directional Deep Brain Stimulation system.
Context
Context
The partnership between Aleva and Inselspital bridges decades of clinical expertise and technological innovation. Together, they established a framework for translating precision microengineering into surgical application — from identifying clinical needs to leading trials that demonstrated significant improvements in symptom control and medication reduction. This collaboration remains a cornerstone of Aleva’s scientific credibility and clinical validation strategy.
The partnership between Aleva and Inselspital bridges decades of clinical expertise and technological innovation. Together, they established a framework for translating precision microengineering into surgical application — from identifying clinical needs to leading trials that demonstrated significant improvements in symptom control and medication reduction. This collaboration remains a cornerstone of Aleva’s scientific credibility and clinical validation strategy.
The partnership between Aleva and Inselspital bridges decades of clinical expertise and technological innovation. Together, they established a framework for translating precision microengineering into surgical application — from identifying clinical needs to leading trials that demonstrated significant improvements in symptom control and medication reduction. This collaboration remains a cornerstone of Aleva’s scientific credibility and clinical validation strategy.
SHARED ENDEAVOURS
SHARED ENDEAVOURS
Clinical Research & Validation
Clinical Research & Validation
A collaboration rooted in shared ambition — combining surgical excellence and engineering precision to improve outcomes for patients with neurological disorders.
Inselspital Overview
Inselspital, University Hospital Bern, is one of Europe’s leading centres for neurosurgery and academic medicine. With a history spanning over 700 years, it serves as a national and international reference in advanced neurological care, clinical research, and medical education. Its Department of Neurosurgery, led by Dr Claudio Pollo, is recognised for pioneering work in movement disorders and Deep Brain Stimulation.
Partnership Highlights
Inselspital provided the clinical environment and neurosurgical leadership that enabled Aleva’s pre-clinical validation and first-in-human study of directional DBS. The collaboration has advanced surgical precision, contributed to peer-reviewed publications — including the landmark Brain (Oxford Academic, 2014) paper — and continues to inform Aleva’s ongoing clinical studies in Europe and the United States.
Inselspital Overview
Inselspital, University Hospital Bern, is one of Europe’s leading centres for neurosurgery and academic medicine. With a history spanning over 700 years, it serves as a national and international reference in advanced neurological care, clinical research, and medical education. Its Department of Neurosurgery, led by Dr Claudio Pollo, is recognised for pioneering work in movement disorders and Deep Brain Stimulation.
Partnership Highlights
Inselspital provided the clinical environment and neurosurgical leadership that enabled Aleva’s pre-clinical validation and first-in-human study of directional DBS. The collaboration has advanced surgical precision, contributed to peer-reviewed publications — including the landmark Brain (Oxford Academic, 2014) paper — and continues to inform Aleva’s ongoing clinical studies in Europe and the United States.
“The collaboration with Aleva reflects the best of clinical science — where technology meets patient need in the operating theatre.”
“The collaboration with Aleva reflects the best of clinical science — where technology meets patient need in the operating theatre.”
— Dr Claudio Pollo, Aleva's Co-Founder & Head of Functional Neurosurgery, Inselspital
— Dr Claudio Pollo, Aleva's Co-Founder & Head of Functional Neurosurgery, Inselspital
“The collaboration with Aleva reflects the best of clinical science — where technology meets patient need in the operating theatre.”
— Dr Claudio Pollo, Aleva's Co-Founder & Head of Functional Neurosurgery, Inselspital
Impact & Shared Achievements
The long-standing partnership between Aleva and Inselspital has redefined how engineering and medicine can co-develop new therapeutic standards. By pairing Aleva’s MEMS-based innovation with Inselspital’s clinical insight, both institutions have contributed to setting a global benchmark for precision neuromodulation and its translation from research to patient care.
Impact & Shared Achievements
The long-standing partnership between Aleva and Inselspital has redefined how engineering and medicine can co-develop new therapeutic standards. By pairing Aleva’s MEMS-based innovation with Inselspital’s clinical insight, both institutions have contributed to setting a global benchmark for precision neuromodulation and its translation from research to patient care.